| Thursday, 1 November 2018 |
| Time/Result | Home | Away | Venue |
| (2) 2-2 (3) |
D.C. |
Columbus | Audi Field |
| 2-3 |
Los Angeles FC |
Real Salt Lake | Banc of California Stadium |
| Sunday, 4 November 2018 |
| Time/Result | Home | Away | Venue |
| 1-0 |
Columbus |
New York | MAPFRE Stadium |
| 2-1 |
Portland |
Seattle | Providence Park |
| 0-1 |
New York City FC |
Atlanta | Yankee Stadium |
| 1-1 |
Real Salt Lake |
Sporting KC | Rio Tinto Stadium |
| Thursday, 8 November 2018 |
| Time/Result | Home | Away | Venue |
| (2) 3-2 (4) |
Seattle |
Portland | CenturyLink Field |
| Sunday, 11 November 2018 |
| Time/Result | Home | Away | Venue |
| 4-2 |
Sporting KC |
Real Salt Lake | Children's Mercy Park |
| 3-1 |
Atlanta |
New York City FC | Mercedes-Benz Stadium |
| 3-0 |
New York |
Columbus | Red Bull Arena |
| Sunday, 25 November 2018 |
| Time/Result | Home | Away | Venue |
| 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET22:00 GMT23:00 22:00 10:00 PM 0:00 KSA9:00 AM AET3:30 (+1) IST5:30 PM VEN2:00 (+1) UAE6:00 AM SST6:00 5:00 3:00 PM MST4:00 PM CST5:00 PM EST17:00 ET17:00 19:00 BRT18:00 |
Atlanta |
New York | Mercedes-Benz Stadium |
| 4:30 PM PT5:30 PM MT6:30 PM CT7:30 PM ET0:30 (+1) GMT1:30 0:30 12:30 AM 2:30 KSA11:30 AM AET6:00 (+1) IST8:00 PM VEN4:30 (+1) UAE8:30 AM SST8:30 7:30 5:30 PM MST6:30 PM CST7:30 PM EST19:30 ET19:30 21:30 BRT20:30 |
Portland |
Sporting KC | Providence Park |
| Thursday, 29 November 2018 |
| Time/Result | Home | Away | Venue |
| 4:00 PM PT5:00 PM MT6:00 PM CT7:00 PM ET0:00 (+1) GMT1:00 0:00 12:00 AM 2:00 KSA11:00 AM AET5:30 (+1) IST7:30 PM VEN4:00 (+1) UAE8:00 AM SST8:00 7:00 5:00 PM MST6:00 PM CST7:00 PM EST19:00 ET19:00 21:00 BRT20:00 |
New York |
Atlanta | Red Bull Arena |
| 6:30 PM PT7:30 PM MT8:30 PM CT9:30 PM ET2:30 (+1) GMT3:30 2:30 2:30 AM 4:30 KSA13:30 AM AET8:00 (+1) IST10:00 PM VEN6:30 (+1) UAE10:30 AM SST10:30 9:30 7:30 PM MST8:30 PM CST9:30 PM EST21:30 ET21:30 23:30 BRT22:30 |
Sporting KC |
Portland | Children's Mercy Park |
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